Mushroom Chicken Alfredo Casserole

Amazing Mushroom Chicken Alfredo Casserole. Chicken fillets with sauteed mushrooms smothered in a rich and creamy homemade Alfredo sauce. This amazing casserole is the perfect comfort food to serve guests or your family.

Mushroom chicken Alfredo casserole recipe in a casserole dish.

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chicken alfredo-

An easy and mouthwatering recipe for homemade alfredo. Chicken tenderloins and sauteed mushrooms in a creamy homemade sauce baked as a casserole. The casserole is so comforting and perfect whenever you’re in the mood for alfredo.

how to make mushroom alfredo casserole-

  • Season chicken.
  • Cook in a pan until chicken is crispy.

Recipe for how to make mushroom chicken Alfredo casserole. How to prepare chicken.

  • Sautee mushrooms, add garlic.
  • Add flour, heavy whipping cream and parmesan cheese, season with salt and pepper.
  • Simmer until the Alfredo sauce thickens.
  • Add chicken to a casserole dish. Pour mushroom Alfredo sauce over the chicken.
  • Bake and enjoy.

How to make this mushroom chicken Alfredo casserole recipe.

what to serve with chicken casserole-

Serve the mushroom and chicken alfredo casserole with a side of buttered pasta noodle (any pasta will work), or mashed potatoes.

can vegetables be added to this casserole-

Yes, you can add your favorite vegetable that you traditionally like to add when preparing alfredo. Broccoli or green beans are a great option.

Creamy chicken alfredo bake with mushrooms.

I hope you love the recipe for this easy and quick casserole.

Try these other PASTA recipes:

Print Recipe
5 from 5 votes

Mushroom Chicken Alfredo Casserole

Mushroom Chicken Alfredo Casserole recipe. Chicken and sauteed mushrooms smothered in a rich and creamy homemade Alfredo sauce. 
Prep Time15 mins
Cook Time45 mins
Total Time1 hr
Course: Main Course
Cuisine: American, Italian
Keyword: chicken alfredo
Servings: 6 servings
Calories: 645kcal
Author: Valentina's Corner



  • 2 lbs chicken fillets
  • 2 Tbsp Olive or Canola oil
  • 1 1/2 tsp table salt
  • 1/4 tsp ground black pepper

Alfredo sauce:

  • 12 oz white mushrooms, sliced
  • 2 Tbsp unsalted butter
  • 3 garlic cloves, minced
  • 1 tsp all-purpose flour
  • cups heavy whipping cream
  • 3/4 cup whole milk
  • 3/4 cup parmesan cheese
  • 1 cup shredded mozzarella cheese, optional


  • Preheat oven to 375°F.
  • Lightly beat chicken with a meat mallet. Season both sides of the chicken with salt and pepper.
  • Heat 1 tablespoon oil in a skillet on high heat, add half of the chicken. Sautee chicken about 5-6 minutes, until golden in color, turn chicken few times. 
  • Repeat with the remaining chicken and another tablespoon oil. Set chicken aside.
  • Add mushrooms to skillet with butter. Sauté until mushrooms are golden, lightly season with salt and pepper.  Add garlic and sauté another minute.
  • Quickly stir in the flour, stir quickly. Add heavy whipping cream and parmesan cheese, stir until well incorporated. Lightly salt and pepper (to taste). Turn heat down to low and allow the sauce to thicken.
  • Add chicken to a casserole dish. Pour mushroom Alfredo sauce over the chicken. Cover with foil.
  • Bake 35 minutes, until Alfredo is bubbling. Remove foil. (If adding shredded cheese, do so at this point). 
    Bake another 10 minutes, until cheese melts. Garnish with fresh herbs. 
  • ENJOY!
Nutrition Facts
Mushroom Chicken Alfredo Casserole
Amount Per Serving
Calories 645 Calories from Fat 441
% Daily Value*
Fat 49g75%
Saturated Fat 26g163%
Cholesterol 238mg79%
Sodium 1107mg48%
Potassium 830mg24%
Carbohydrates 6g2%
Sugar 1g1%
Protein 44g88%
Vitamin A 1555IU31%
Vitamin C 4mg5%
Calcium 306mg31%
Iron 1.1mg6%
* Percent Daily Values are based on a 2000 calorie diet.

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Show 16 Comments
  • Dana 04/28/2018, 10:20 pm Link Reply

    If I want to do it on Saturday and bake it on Sunday, how is better to do it? Should I make the sauce and keep it in a fridge ?

    • admin 05/01/2018, 11:39 am Link Reply

      Hi Dana, you can completely prepare everything per instructions and just bake Sunday. You’ll just need to bake a little longer than indicated since it will be cold (since it was refrigerated). You’re going to love this recipe. 🙂

  • Julie 11/06/2017, 4:45 pm Link Reply

    Hi, this looks delicious! Just wondering if you have ever added al dente cooked pasta to the casserole before baking (like lasagna) to make it even more “make ahead”. Looks like there is plenty of sauce in the casserole to accommodate the pasta? Thanks!

    • admin 11/07/2017, 2:00 am Link Reply

      Hi, Julie. I usually cook the pasta, drain it and close in Tupperware. Then just pour boiling water over the pasta before serving or heat in a skillet. Never thought of adding the pasta to the casserole but is a wonderful idea. Hhhmm. I’ll need to try that, or if you do before me, let me know how it turns out?.
      P.S. you need to try this asap – it’s phenomenal. 🙂 🙂

  • Lena 11/11/2016, 9:58 pm Link Reply

    Made this today. .. delicious! Thank you for the recipe!

    • admin 11/12/2016, 11:43 pm Link Reply

      That’s wonderful to hear. Thank you for visiting and the feedback Lena..??

  • Maria 03/10/2016, 6:53 pm Link Reply

    Thank you! Made with thin spaghetti out of the world the best alfredo ever 🙂 🙂 🙂

    • admin 03/10/2016, 7:38 pm Link Reply

      You’re so sweet Maria!!! <3 Soooooo glad you enjoyed it!!

  • Sweet Somethings Blog 03/10/2016, 4:19 pm Link Reply

    Oh this looks delicious. I also love ALL italian food, including delicious, creamy, cheesy and bad for you chicken alfredo! Haha.

    • admin 03/10/2016, 7:39 pm Link Reply

      Same here hon!!!!! 🙂

  • Veronica 03/10/2016, 9:08 am Link Reply


    • admin 03/10/2016, 1:18 pm Link Reply

      Thanks for the great feedback Veronica. We love Alfredo as well. So happy you enjoy what we enjoy:)..

  • Maria 03/10/2016, 8:52 am Link Reply

    I want to make it today! What can I serve it with pasta ,rice or what would be best? 🙂

    • admin 03/10/2016, 1:16 pm Link Reply

      Our kids love it with angel hair pasta (or any other pasta). Hubs loves it with mashed potatoes. Hope you enjoy it.

  • Maria 03/09/2016, 9:23 pm Link Reply

    Omg this looks soooooo good, making me hungry :)!!I will make it this week!

    • admin 03/09/2016, 10:24 pm Link Reply

      Maria, yaaay, you’re in for a treat!:)

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